*Birds that have been put down because of avian influenza. (Photo by* *Roee Shpernik*)

A reader sent me a link to the following:

Japan Creates Frankenstein Bird Flu Virus With New Immunological Traits
August 1, 2025
Japanese researchers engineered an entirely new strain of bird flu, combining the genetic material of two separate wild viruses to create what they call Vac-3: a pathogen that is “a reassortant virus between A/duck/Hokkaido/101/2004 (H5N3) and A/duck/Hokkaido/262/2004 (H6N1).”
This lab-built virus—A/duck/Hokkaido/Vac-3/2007 (H5N1)—was never observed in nature. …
The new study comes after NIH-funded researchers at the University of Georgia, Mount Sinai, and Texas Biomed were caught engineering lab-made H5N1 bird flu viruses—one of which killed 100% of exposed mammals—using synthetic DNA constructs and then deliberately infecting live dairy cows, all under the same $59 million federal contract that has also been tied to mammal-adapted, drug-resistant strain development.
Japan is also working with U.S. scientists on other projects to build lab-made horse-human influenza hybrids that replicate 100 times faster than natural strains using aborted fetal cells engineered with the cancer-linked SV40 virus, also under the banner of vaccine development.
All of these developments raise fears that another man-made pandemic is on the horizon, as Congress, the White House, the Department of Energy, the FBI, and the CIA have acknowledged that a lab-related incident involving gain-of-function research is most likely the origin of COVID-19. …
While the researchers don’t use the phrase “gain-of-function” that’s effectively what this is: the creation of a chimeric virus with novel immunological features.
The Vac-3 strain was not isolated in the wild.
It was constructed by merging influenza genes from unrelated alleged viruses, giving the final product new, enhanced abilities—especially in triggering memory immune responses.
A White House Executive Order from May 2025 defines “dangerous gain-of-function research” as scientific work on infectious agents that can cause disease by enhancing their pathogenicity or transmissibility.
Importantly, the Order explicitly includes research that can:
“[disrupt] beneficial immunological response or the effectiveness of an immunization against the agent or toxin” (meaning altering how the immune system responds to the virus), and,“[enhance] the susceptibility of a human host population to the agent or toxin.”
This means that GoF research includes altering the virus in ways that affect the immune response—either by weakening it or by increasing the harm caused through immune interaction.
So, engineering a virus to produce a stronger or otherwise altered immune response in hosts falls under this definition because it modifies the virus’s interaction with host immunity, which could have significant health consequences. https://www.zerohedge.com/medical/japan-creates-frankenstein-bird-flu-virus-new-immunological-traits

While researchers hope that there will be a benefit to what they are doing there are also risks.

In Brazil, they are modifying mosquitoes so that they cannot pass Dengue fever:

There are factories in Brazil where one of the most reviled creatures known to humans is being bred intentionally by the millions – mosquitoes. Now, the folks who work in these high-tech factories will tell you these are not your grandmother’s mosquitoes. They are actually designed to protect people from the diseases that mosquitoes carry. It’s a major investment for Brazil, one that other countries, especially in the Americas, are keeping an eye on. https://www.iowapublicradio.org/2025-07-31/brazil-aims-to-reduce-dengue-with-modified-mosquitoes

There look to be potential benefits from this, but there are also risks.

That said, the release of genetically-modified mosquitoes had been tried years before in Brazil, but the results were not as the proponents hoped:

Deadly ‘super mosquitoes that are even tougher’ accidentally created by scientists after bungled experiment
Updated September 18, 2019
GENETICALLY modified mosquitoes that were designed by scientists to help populations decrease are actually thriving.
This is according to new research that claims the plan to create gene-hacked mosquitoes that have offspring which die immediately has spectacularly backfired and now scientists don’t know what will happen next.
The modified mosquitoes were released in Jacobina in Brazil and were supposed to mix with the local population and decrease numbers with their weak offspring genetics.
Although the wild population did plummet for a short while, 18 months later it was right back up again.
This is mostly concerning because scientists think the new ‘super mosquitoes’ have properties that might make them harder to kill.
Research about the pests has been published in the journal Nature Scientific Reports. …
Mosquitoes like the Aedes aegypti variety that was edited can carry dangerous diseases like yellow fever, Zika virus and Malaria.
This is why efforts are being made to reduce their numbers.
However, now traces of the genetically modified genes have been found in the natural population.
This means they are successfully interbreeding. …
The offspring of the gene-hacked mosquitoes and the natural ones are thought to be more robust but whether they pose a threat is unknown.
Researcher Jeffrey Powell told News Atlas: “It is the unanticipated outcome that is concerning.” https://www.thesun.co.uk/tech/9947305/deadly-super-mosquitoes-accidentally-created/

So, at least some scientists have been concerned about “the unanticipated outcome.” Having mosquitoes that are “more robust” makes them harder to kill and, thus tends to increase their longevity.

Well, I anticipated something just like this when I reported about the release of GMOs mosquitoes on July 28, 2018. Here are some of my posted warnings.

Mosquitoes can carry and spread many diseases.
But releasing genetically-modified ones into the wild presents unknown risks.
One assumption that scientists have tended to make with genetically-modified organisms (GMOs) is that if they do not see any dangers, then there are none. That is foolish, yet that continues to be the view of the pro-GMO crowd.
While there certainly are risks associated with contracting the Zika virus (see Zika is more dangerous than many thought; USA has its first Zika death), this ‘solution’ poses risks to various parts of the ecosystem as well as the possibility that some of the offspring produced will have greater longevity as opposed to greatly reduced longevity.
The vast quantity of mosquito offspring increases the possibility that there will be some that have the opposite traits that the GMO crowd is hoping to get. And if this occurs, this could cause much greater problems than the GMO ‘solution’ was supposed to fix. …
Genetically modified mosquitoes pose dangerous risks. (Thiel B. Genetically-modified mosquitoes have been released to ‘fight Zika’. COGwriter, July 28, 2018)

GMOs are very dangerous precisely because scientists CANNOT ANTICIPATE all the potentially negative outcomes. IT IS NOT SCIENTIFICALLY POSSIBLE FOR TO KNOW ALL THE RISKS, yet these experiments with genetically-modified mosquitoes in the wild continue.

And while I suspect that malaria will be brought under control for a while, and genetically-modified mosquitoes could play a role, the fact is that super-mosquitoes are a health-risk.

The Dengue project is a bit different in that it is not quite the GMO method.

I suspect that some of these projects WILL BE considered to be successful, which will result in more of them being worked on.

Yet, mosquitoes, GMO or otherwise, have major potential to spread pestilences and cause pandemics.

Consider that the Bible shows that the coming European King of the North beast will gain power after a time of death and pestilence.

While COVID-19 itself was not that, it has helped set the stage for people to turn to such a leader.

We put together the following video on our Bible News Prophecy YouTube channel:

14:53
Biological Weapons and the 4th Horseman of the Apocalypse
Tucker Carlson interviewed Democratic presidential party candidate Robert F. Kennedy, Jr. (RFK). During that interview, RFK asserted that the United States has had thousands of scientists working on making bioweapons. Officially, the USA has denied this as it is a party to the Biological Weapons Convention. RFK states that Anthoy Fauci was responsible for biological weapons development. Does the ‘Global South’ consider that the West may intend to exterminate people through biological warfare? Did Jesus prophesy pestilences? Have humans engaged in biological or germ warfare for millennia? What were some things that Raymond McNair warned about over 50 years ago? Can we trust scientists to totally, safely control all the infectious agents they work with? Could humankind be developing, knowingly or unknowingly, biological agents that could be responsible for many of the deaths that are prophesied to occur with the ride of the ‘pale horse of death,’ which is the fourth of the four horsemen of the Apocalypse to ride? Steve Dupuie and Dr. Thiel address these matters.

Here is a link to our video: Biological Weapons and the 4th Horseman of the Apocalypse.

Biological pathogens developed by humans are a real threat.

We are getting closer to the time of major pestilences and international government controls.

Humans, directly or indirectly, will be a factor in the coming more severe pestilences.

Some items of possibly related interest may include:

The New Testament Church, History, and Unclean Meats Are foods considered to have been unclean in the Old Testament considered to be food in the New Testament? This article discusses this from the perspective of the New Testament. It also has a list of clean and unclean animals. It also answers the question, is pork healthy or is pork dangerous? There is also a sermon-length video on this: Christians and Unclean Meats; three short videos are also available: Did Jesus declare all animal flesh food?, Should Christians Eat Insects?, and COVID, Pandemics, and Unclean Meat.
GMOs and Bible Prophecy What are GMOs? Since they were not in the food supply until 1994, how could they possibly relate to Bible prophecy? Do GMOs put the USA and others at risk? Here are some related videos: GMO Risks and the Bible and GMOs, Lab meat, Hydrogenation: Safe or Dangerous?
Chimeras: Has Science Crossed the Line? What are chimeras? Has science crossed the line? Does the Bible give any clues? A video of related interest is Half human, half pig: What’s the difference? and Human-Monkey Embryos and Death.
Four Horsemen of the Apocalypse What do each of the four horseman of the Apocalypse represent? Have they began their ride? Did Jesus discuss the any of this? Might their rides coincide with the “beginning of sorrows? Do they start their ride prior to the Great Tribulation? Did Nostradamus or any other ‘private prophets’ write predictions that may mislead people so that they may not understand the truth of one or more of the four horseman? There is also a related YouTube video titled Sorrows and the Four Horsemen of the Apocalypse. Here is a link to a shorter video: These Signs of the 4 Horsemen Have Begun.
Biological Warfare and Prophecy Is biological warfare possible? Was it prophesied? Scientists have long warned that pathogenic organisms like the coronavirus could be weaponized. Furthermore, back in 2017, there were concerns that the biological research facility being constructed in Wuhan, China was risky and that a coronavirus from it could be released. On January 25, 2020, China’s President Xi Jinping publicly stated that the situation with the Wuhan-related strain of the coronavirus was grave. Did Church of God writers like the late evangelist Raymond McNair warn that engineered viruses (the “Doomsday bug”) were consistent with prophecies from Jesus? Did a warning from CCOG leader Bob Thiel warn about risks of genetically-modified (GMO) mosquitoes come to pass? Could human research and/or the consumption of biblically-unclean animals such as bats and snakes be a factor in current outbreaks or coming future pestilences? What about famines? How devastating have pestilences been? How devastating are the prophesied ones going to be? Dr. Thiel addresses these issues and more in this video.
When Will the Great Tribulation Begin? 2024, 2025, or 2026? Can the Great Tribulation begin today? What happens before the Great Tribulation in the “beginning of sorrows”? What happens in the Great Tribulation and the Day of the Lord? Is this the time of the Gentiles? When is the earliest that the Great Tribulation can begin? What is the Day of the Lord? Who are the 144,000? Here is a version of the article in the Spanish language: ¿Puede la Gran Tribulación comenzar en el 2020 o 2021? ¿Es el Tiempo de los Gentiles? A related video is: Great Tribulation: 2026 or 2027? A shorter video is: Tribulation in 2024? Here is a video in the Spanish language: Es El 2021 el año de La Gran Tribulación o el Grande Reseteo Financiero.